Never before has the bar for business success been higher: companies operate in an increasingly competitive global business environment and they are also expected to conduct their business in a way that does not cause harm for people or the planet. In a world that is increasingly interconnected and transparent, companies are not only accountable to national laws and regulations, but also to public expectations. Images from tragic accidents in textile factories in Bangladesh, child labor in cobalt mines in the Democratic Republic of the Congo, or forced labor of Uighurs in Chinese cotton fields, are shocking consumers and investors and they raise questions about the role of companies to prevent such human rights violations. However, today’s business models are often in conflict with public expectations and human rights in particular seem to present paradoxical management challenges. Is it possible for companies to integrate human rights in core operations while running a successful business?